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Clinical Evidence for Weight Loss and Metabolic Health A Phase 2 trial published in NEJM (2023) reported approximately 24.2% mean body weight reduction over 48 weeks at the highest dose, alongside improvements in fasting glucose, insulin sensitivity, triglycerides, and waist circumference

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(iv) prevention and/or treatment of cardiovascular diseases, such as delaying or reducing development of a major adverse cardiovascular event (MACE) selected from the group consisting of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, revascularisation, hospitalisation for unstable angina pectoris, and hospitalisation for heart failure

Cardiovascular outcomes with tirzepatide versus dulaglutide in type 2 diabetes

Millions of Americans take semaglutide for weight loss, and many wonder if they can bring their injections on flights