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Patients are supposed to take the drugs continually, since the benefits for blood sugar and weight loss wane when treatment stops

New England Journal of Medicine, 393 (18), 17961806

10.1001/jama.2018.18269 66

Nausea may be due to delayed gastric emptying, and abdominal distention and constipation may be due to delayed intestinal motility, but the reason for the diarrhea is unclear