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Estos efectos se atribuyen a su mecanismo dual de accin sobre los receptores GIP y GLP-1

Furthermore, in a 12-week RCT in which patients were either assigned to liraglutide (1.8 mg/day), sitagliptin (100 mg/day) or placebo, no difference in glycemic control or bodyweight reductions were found, and both treatments failed to reduce liver hepatic fat content compared to placebo (69)