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Additionally, the updated model included covariates on oral absorption parameters estimated in the current analysis, which were: body weight (continuous), post-dose fasting time (15, 30, 60, 120, 240, 300 min) and water volume (50, 120, 240 mL) for F , and post-dose fasting time for k a

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GHK-Cu (copper tripeptide-1) and tretinoin (all-trans retinoic acid) are two of the most discussed anti-aging actives in dermatology, yet they belong to entirely different families and sit on opposite ends of the regulatory spectrum