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The gradual dosing schedule helps minimize side effects and improves tolerability

Alternative Treatments: If Rybelsus is discontinued due to lack of efficacy, intolerable side effects, or other reasons, your healthcare provider may recommend alternative treatments for managing type 2 diabetes

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[14] [15] ICH Q2(R2), Q3A(R2), and Q3C(R9) are pharmaceutical-development documents and do not directly define mandatory specifications for research-use-only GSH