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In sym40-1 nodules treated with 0.1 mM GSH, the expression of Abr17 and 7RA84 was downregulated (Supplementary Figure 4B)

This impairment in mitochondrial function enhances ROS generation and oxidative stress, resulting in damage to neuronal proteins, lipids, and DNA

A byproduct of oxidation is the creation of free radicals, which are unstable molecules that can damage cell DNA and potentially cause permanent mutations

Some studies have encapsulated phenolic antioxidants in nanoliposomes, which not only effectively maintain the stability of the active ingredients but also improve their bioavailability (252)