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Because of their devastating effects in agriculture, PPNs are well-studied, and hundreds of secreted effectors have been identified, though, similar to other nematodes, few have been studied in mechanistic detail (Rehman et al., 2016

However, while these mechanistic insights are promising, the translation into robust clinical outcomes remains limited, and current evidence is largely derived from in vitro and animal models (123125)

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Then false discovery rates (FDR) were calculated for metabolites by the q-value R package ( via the GOplot R package ( Results Clinical characteristics of study participants Clinical characteristics of patients were shown in Table 1