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Long-acting agents (weekly formulations, liraglutide daily) provide sustained GLP-1 activity day-long, improving fasting and postprandial glucose with less fluctuation

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RA patients have compositional and functional alterations in the gut microbiota (GM) (Zhang et al., 2015), and a significant decrease in microbial diversity compared with healthy controls has been reported (Chen et al., 2016)

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The examination should also include observation for a palpable defect and the Thompson test (squeezing the calf, which should result in plantar flexion in an attached tendon) to rule out rupture of the Achilles tendon