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Regarding -GluCys, however, significant differences between control and patient groups were observed in both non-smoking ( p = 5.71E-07) and smoking patients ( p = 0.0152, Bonferroni test)

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Most published work has used in-vitro gastrointestinal models and tendon and ligament cell lines to examine these mechanisms

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While rCMRglc increases in prefrontal cortical areas have been associated with analgesic and antidepressant effects of ALCAR and KET, the marked metabolic increases KET induces in limbic and dopaminergic areas have been related to its psychotomimetic and abuse properties