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Gut 2005

Mild nausea or lightheadedness, especially during the first week Injection site discomfort, redness, or swelling Headache Rare: water retention or joint stiffness Your lab results could reveal changes in your hormones that require follow-up

In the lipopolysaccharide (LPS)-induced acute abdominal inflammation model, lactoferrin utilizes its anti-inflammatory effects via reducing levels of the macrophage-related chemokines Ccl5 and Ccl2, as well as highly activated p65 signaling in lactoferrin supplemented mice, which is in charge of elevated levels of Ccl5 and Ccl2 expression by inhibiting NF-KB signaling

They also exhibit lower incidences of cancer and extended lifespans [3]

No published human study tracks continuous use beyond 12 weeks, making extended unsupervised administration an undocumented risk with the current state of evidence on BPC-157