VHLL Rabbit Polyclonal Antibody, 100ul Transporters Regulator of G protein signaling

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins

Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy

Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains

Guanylate cyclase soluble subunit alpha-3 encoded by GUCY1A3 is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme

VHLL Rabbit Polyclonal Antibody, 100ul Transporters Regulator of G protein signaling