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When this ratio collapses, the cell enters a state of severe oxidative stress, leading to accelerated aging, mitochondrial dysfunction, and eventually, cellular death (apoptosis)

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Diese indirekte Modulation unterscheidet es von pharmakologischen Sedativa und rckt es in den Fokus der Forschung zu neuroregulatorischen Peptiden

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Cells were loaded with MitoTracker Red dye (Excitation/Emission: 579/599 nm) at 100 nM final concentration (37 C for 15 min) mounted in Live Cell Imaging Solution (Thermo Fisher), and viewed under a laser confocal microscope (LSM 510