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Miyagawa I, Nakayamada S, Nakano K, Yamagata K, Sakata K, Yamaoka K, Tanaka Y

Doxepin is converted to the active metabolite desmethyldoxepin by N -demethylation and to other inactive metabolites in liver (Ziegler et al., 1978), and CYP2D6 and CYP2C19 are the main enzymes involved in this metabolism, with CYP1A2 and CYP2C9 involved to a lesser extent (Kirchheiner et al., 2002

Contains NO artificial color, sugar, salt, wheat, gluten, soy, milk, egg or prese

These pollutants don't simply rest on the skin's surface

The COA provides analytical documentation verifying key characteristics of the compound before it is released for distribution