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Clinical studies have shown impressive weight loss outcomes, with an average reduction of 15.0% to 20.9% body weight in adults without diabetes over 72 weeks, depending on the dosage Safety profile : While Zepbound offers promising results, it also comes with potential side effects, ranging from gastrointestinal issues to thyroid C-cell tumors

Science-Backed How Tirzepatide works Tirzepatide is a first-in-class dual-agonist, activating both GLP-1 and GIP hormone receptors to powerfully regulate appetite, blood sugar, and fat metabolism

This is a boxed warning for the GLP-1 class and Retatrutide carries the same precaution

In a clinical trial of 2539 participants, those using tirzepatide over 72 weeks experienced weight loss, with averages of 15% for the 5 mg dose, 20% for the 10 mg dose, and 21% for the 15 mg dose, compared with a 3% reduction in the placebo group