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"Triple-hormone-receptor agonist retatrutide for obesityA phase 2 trial." New England Journal of Medicine , 389(6), 514-526

Commenting on the study for the UK Science Media Centre, Dr Marie Spreckley, a postdoctoral researcher at the University of Cambridge specialising in obesity and incretin-based therapies, noted: The magnitude of these genetic effects is small in clinical terms

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Roche paid 1.65 billion dollars upfront for the rights, a measure of the interest in amylin-based mechanisms as an alternative or complement to GLP-1 drugs