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Retinoids remain gold standard for collagen stimulation through retinoic acid receptor activation

Hay dos estrategias principales para lograrlo: reducir gradualmente las dosis y espaciarlas

doi:10.1016/j.molmet.2019.09.010 4

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However, CDT requires intensive specialist input from certified lymphedema therapists, patient compliance is often suboptimal due to the demanding regimen, and long-term outcomes remain variable