TM199 Rabbit Polyclonal Antibody, 20ul Culture Plate Inserts This difference in size is

This difference in size is largely due to an increase in the number of subdomains

Multiple transcript variants encoding different isoforms have been characterized for this gene

The encoded enzyme contains a hydrolase domain at the N-terminal portion

and the truncated form additionally interacts with CCR1 and CCR2

TOP2A encodes a DNA topoisomerase

TM199 Rabbit Polyclonal Antibody, 20ul Culture Plate Inserts This difference in size isThe protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER) Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) in some human cells. The encoded protein shares some homology with the yeast protein Vma12. Defects in this gene are a cause of congenital disorder of glycosylation type IIp.