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Elevated serum B12 levels often indicate underlying conditions such as haematological disorders, liver disease, or renal impairment rather than toxicity from supplementation

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Neurotoxicology 55, 4857

A useful protocol records storage temperature, reconstitution conditions, time in solution, freeze-thaw history, vial appearance, and any analytical checks performed before use

Valenzuela R, Echeverria F, Ortiz M et al (2017) Hydroxytyrosol prevents reduction in liver activity of -5 and -6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice