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DBS efficacy has improved with adaptive stimulation protocols 28 and advanced neuroimaging 29 , but existing targets have shown limited success in improving levodopa-resistant freezing of gait and may lead to adverse effects, such as cognitive impairment 26,30

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Akaras N, Kucukler S, Gur C, Ileriturk M, Kandemir FM (2024) Sinapic acid protects against lead acetate-induced lung toxicity by reducing oxidative stress, apoptosis, inflammation, and endoplasmic reticulum stress damage

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