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References [1] Collins, L., & Costello, R

Together they hit oxidative stress harder than either one alone

Notoginsenoside Ft1 inhibits the PI3K/AKT/mTOR signaling pathway, activates the p38 MAPK and ERK1/2 signaling pathways, and increases the proportion of CD8 cells, thereby inducing + T apoptosis and lysosomal cell death in various cancer cells, and promoting angiogenesis

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23 NADPH is also needed for dihydrofolate reductase (DHFR) enzyme to catalyze the reduction of dihydrofolate to tetrahydrofolate (THF) in folate metabolism, which is required for de novo biosynthesis of thymidylate, purines, methionine, and some amino acids