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The effectiveness of these administration strategies depends on various factors, including bioavailability, drug formulation, gastrointestinal conditions, and systemic distribution, which, if not optimized, could compromise therapeutic outcomes and limit the antibiotics efficacy against targeted infections (McCarthy and Avent, 2020

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Epitalon-treated oocytes, however, showed reduced Annexin-V signals and a lower proportion of apoptotic cells, indicating that the peptide reduces apoptotic susceptibility in aged oocytes [2]