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Available from: Accessed 21 March, 2019

Methods Cell line and treatments The rat intestinal epithelial cell line IEC-6 [32] was obtained from the National Infrastructure of Cell Line Resource (Beijing, China)

Imipridones ONC201 and ONC212 were kindly provided from Chimerix (Durham, NC)

Therasse P, Vansteenkiste JF, Zielinski M, DePas TM, Atanackovic D, Swquist LV, Vallieres E, Swisher SG , Adams S, Passlick B, Eberhardt WEE, Grunenwald D, Mok T, Boyer M, Katz A, Douillard JY, Debois M, Brichard VG, Altorki NK