AIF1 Polyclonal Antibody, 50ul Endonucleases & Exonucleases It appears to function as

It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization

RCC2/TD-60 is required for spindle assembly and recruitment of survivin and aurora B

siRNA binds to target mRNA in the RISC complex to inhibit its function

and defects in cardiac conduction

There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes

AIF1 Polyclonal Antibody, 50ul Endonucleases & Exonucleases It appears to function asThis gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full length and coding nature of some of these variants is not certain.