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The advent of high-throughput sequencing techniques has conducted to the classification of breast cancer into different molecular subtypes corresponding to the luminal cancers expressing the estrogen and progesterone receptors (ER and PR, respectively), those over-expressing the HER2/Erb2 receptor (HER2), and the triple negative breast cancer (TNBC) characterized by the absence of expression of ER, PR, and HER2 [2]