TIC10 isomer Catalog No.:M9715-2 The PARP family of proteins

The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway

It was originated by Roche but as of 2008 is sold by Meda AB under the trade name Mobiflex

CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)C1=CC2OCCOC=2C=C1

PMPA increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice

749234-11-5

TIC10 isomer Catalog No.:M9715-2 The PARP family of proteinsTIC10 isomer is an isomer and the "inactive version" of TIC10. TIC 10 isomer was introduced to the research community since it was structurally wrong assigned as the bioactive TIC 10 during early stage development of TIC 10 (now called ONC 201). TIC 10 isomer was found to be inactive, which did not reduce the viability of cancer cells. TIC 10 isomer may be used as a reference compound to compare with ONC 201. Product information CAS Number: 41276 02 2