PUR4 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays Expression of the human protein

Expression of the human protein has been detected in uterus

which results in the inhibition of the mammalian target of rapamycin protein

Multiple alternative splice variants have been described

In functional expression studies

The active| hypophosphorylated form of the protein binds transcription factor E2F1

PUR4 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays Expression of the human proteinPurines are necessary for many cellular processes including DNA replication transcription and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.