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Thus, GLP-1 treatment improved the diversity of gut microbiota, increased the bacterial species traditionally associated with beneficial effects on the host (Lactobacillaceae and Bifidobacteriaceae), and decreased the bacterial species traditionally associated with harmful effects (Bacteroides and Ruminococcaceae)

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GLP-1 receptor agonists may reduce inflammation through direct mechanisms (modulating immune cell function, reducing oxidative stress) and indirect effects from weight loss and improved metabolic control

To support this observation, we performed factorial ANOVA including sex as a between-subject factor (Table 1-Table 14)

Many participants were identified by several metabolic biomarkers