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These findings have great translational relevance and suggest that, as a potential treatment for opioid use disorder, the effects of semaglutide on symptoms of opioid withdrawal may be of lesser benefit to patients with more severe OUD compared to mild or moderate

Recent clinical observations suggest GLP-1 receptor agonists may influence migraine patterns in some patients, though evidence is still developing

Semaglutide in the form of Ozempic is no longer available off-label for weight loss and is only approved for patients living with type 2 diabetes

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