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PGP9.5 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Amplification It encodes the branched-chain acyl-CoA

SKU: 34841555757

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PGP9.5 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Amplification It encodes the branched-chain acyl-CoAThe protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

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Description

It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes

A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria

Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described

The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport

It does not have a mouse homolog

PGP9.5 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Amplification It encodes the branched-chain acyl-CoAThe protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

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