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Sattar N, Petrie MC, Zinman B, Januzzi JL Jr

It's critical because it: Minimizes side effects like nausea and GI discomfort Lets your body adjust to the medication Helps find your optimal therapeutic dose Most patients step up roughly every 4 weeks over a 1216 week schedule until reaching a maintenance dose which keeps side effects down while supporting results

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In certain circumstances (such as hemorrhage and trauma), the BBB can be impaired, thus allowing greater penetration of IV DFO into the brain (Li et al., 2022)