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Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression NFKB1 encodes a 105 kD

SKU: 45656589800

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Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression NFKB1 encodes a 105 kDThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

NFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

NEK9 (NIMA related kinase 9) encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases

The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation

This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4

three ANK repeats

Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression NFKB1 encodes a 105 kDThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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