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JAMA Cardiol 2017;2:10259

Key dangers include: Overdose or underdose: Errors in calculation can result in receiving far more or far less than the intended amount, leading to severe adverse effects or no therapeutic benefit Microbial contamination: Without pharmaceutical-grade manufacturing conditions, vials may be contaminated with bacteria or fungi, risking serious infection including sepsis Chemical degradation: Improper storage, incorrect diluent, or excessive agitation can degrade the peptide, producing unknown breakdown products Injection site complications: Subcutaneous injections performed without training can cause lipodystrophy, abscess formation, or nerve injury There is also a psychological dimension to consider

Sport Tested: Informed Sport 0g 0g 0g 0mg 0g 0g Nutrition Facts 60 Servings Serving Size: 1 Capsule Serving Per Container: 60 * Percent Daily Values are based on a 2,000 calorie diet

Additionally, a placebo-controlled, phase 2 study assessed the efficacy and tolerability of tirzepatide treatment using three different escalation schemes with longer time intervals between dose escalations and different dose escalations to attain doses as high as 15 mg in patients with type 2 diabetes (21)

2017 Apr;51(4):30011