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Thus, inhibition of mevalonic acid production also results in lower CoQ10 levels as well as a reduction in dolichols and isoprenylated proteins that are involved in cellular respiration and muscle cell functioning

Following xenobiotic exposure, the Nrf2/Keap1 pathway is activated, releasing Nrf2 and causing it to translocate into the nucleus where it forms a heterodimer with its partner sMAF oncogene homolog