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Clinical trials on this specific drug have been limited, and it is currently classified under Pregnancy Category C by the Food and Drug Administration (FDA)

Thus, poly-agonist drugs may complement classical incretin actions on NASH pathophysiology, providing a promising therapeutic approach

Upregulation of DPP-4 in hepatocytes is linked to hepatic insulin resistance and liver steatosis as observed in rats, Citation73 whereas knocking down DPP-4 optimizes insulin sensitivity and lowers lipid buildup in cultured hepatocytes

Participants also noted an improved ability to resist any cravings that emerged during the study