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Over a mean (SD) follow-up of 2.2 (1.9) years, the annual rate of acute healthcare utilization was 10% lower in the GLP1-RA group compared to active comparators

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Limitations of this approach, however, include the lack of quantitative analysis and of a structured assessment of the quality of studies and certainty of evidence, which were beyond the scope of this descriptive work

doi: 10.1210/jc.2018-02281 37 Espinosa-de-los-MonterosALGonzalezBVargasGSosaEMercadoM

Regarding the rest of the biomarkers, univariate ANCOVA with BMI adjustment was used with variables fitting a normal distribution and the Mann Whitney U test for those not fitting the normal distribution