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Common Side Effects and What to Watch For The most common side effects are gastrointestinal including nausea, vomiting, and diarrhoea and are typically mild to moderate

GLP-1 receptor agonists modulate dopaminergic signaling by increasing dopamine--hydroxylase levels, reducing dopamine release, enhancing dopamine transporter expression, increasing dopamine turnover, and suppressing NAc projections, which attenuates phasic dopaminergic signaling and reduces consummatory behaviors (Vallf et al., 2016