PUR6 Rabbit Polyclonal Antibody, 100ul Cellular Cultivation & Health Management LIM domain kinase 2 by

LIM domain kinase 2 by LIMK2 is phosphorylated and activated by ROCK

the encoded protein may not have any proteolytic activity

and is a key regulator of xenobiotic and endobiotic metabolism

The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner

Polymorphisms in this gene may be associated with susceptibility for migraine headaches

PUR6 Rabbit Polyclonal Antibody, 100ul Cellular Cultivation & Health Management LIM domain kinase 2 byThis gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway and transcription of the two genes is coordinately regulated. The human genome